[ti:Africa Wants Malaria Vaccine Soon] [by:www.21voa.com] [00:00.00]更多听力请访问21VOA.COM [00:00.04]The African Union's top health official [00:03.60]wants to get the world's first approved malaria vaccine [00:08.68]to African countries as soon as possible. [00:12.72]This comes one day after the World Health Organization (WHO) [00:18.96]said the vaccine should be given to children [00:22.36]across Africa to stop the spread of the disease. [00:27.72]John Nkengasong is the director of Africa Centers [00:31.88]for Disease Control and Prevention. [00:34.64]He told an online news conference Thursday, [00:39.00]"We will be engaging with GAVI the vaccine alliance [00:43.40]and WHO in the coming days [00:47.12]to understand first of all the availability of this vaccine." [00:53.04]He noted that by the end of 2021, [00:56.80]malaria will likely have killed many more people in Africa [01:01.48]than COVID-19 will have. [01:05.12]WHO Director-General Tedros Adhanom Ghebreyesus [01:10.48]called it "a historic moment" Wednesday [01:13.88]after the health agency's advisory groups [01:17.20]approved the use of a vaccine to fight malaria. [01:22.48]Dr. Matshidiso Moeti is the WHO's Africa director. [01:28.92]She said, "We expect many more African children [01:33.24]to be protected from malaria and grow into healthy adults." [01:38.96]The WHO said its decision was based largely on results [01:44.16]from ongoing research in Ghana, Kenya and Malawi. [01:50.32]The research followed more than 800,000 children [01:54.16]who have received the vaccine since 2019. [01:58.96]The WHO said side effects were rare, [02:02.56]but sometimes included a high temperature that could result [02:07.28]in temporary sudden movements called convulsions. [02:12.12]The vaccine, known as Mosquirix, was developed [02:16.44]by British drugmaker GlaxoSmithKline in 1987. [02:22.32]While it is the first to be authorized, [02:24.76]the vaccine is only about 30 percent effective. [02:30.04]It requires up to four treatments [02:33.00]and its protection decreases after several months. [02:37.92]But scientists say the vaccine could have a major effect [02:42.32]against malaria in Africa. [02:45.84]Most of the world's 200 million cases [02:49.12]and 400,000 malaria deaths each year are in Africa. [02:55.00]Julian Rayner, director of the Cambridge Institute [02:59.28]for Medical Research, said, "It's an imperfect vaccine, [03:03.72]but it will still stop hundreds of thousands of children from dying." [03:09.32]Dr. Alejandro Cravioto [03:11.96]is head of the WHO vaccine group that gave the guidance. [03:17.40]He said designing a shot against malaria was difficult [03:22.60]because it is a parasitic disease spread by insects called mosquitoes. [03:29.92]"We're confronted with extraordinarily complex organisms," he said. [03:34.68]"We are not yet in reach of a highly efficacious vaccine, [03:39.68]but what we have now is a vaccine [03:42.76]that can be deployed and that is safe." [03:46.64]Azra Ghani is chair of infectious diseases [03:50.56]at Imperial College London. [03:53.64]She said the WHO guidance would hopefully [03:58.16]be a "first step" to making better malaria vaccines. [04:03.60]She added that efforts to produce a second-generation malaria vaccine [04:09.72]could receive help from messenger RNA technology. [04:14.60]The drug company BioNTech recently said [04:18.16]it would begin researching for a possible malaria vaccine. [04:22.88]The company and its partner Pfizer [04:26.48]made one of the most successful COVID-19 vaccines with mRNA. [04:33.28]I'm Caty Weaver. [04:34.56]更多听力请访问21VOA.COM